Pharmacogenetics in the clinic

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Pharmacogenetics in the clinic

Pharmacogenetics is one of the first clinical applications of the postgenomic era; it studies the role of heritability of drug responses. It promises personalised medicine rather than the established ‘one size fits all’ approach to drugs and dosages. This should ultimately lead to more efficient and safer drug therapy. In recent years, pharmacogenetic information has been included in drug label...

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Designing a therapeutic plan that involves the least risk of toxicity and the greatest chance of success is the goal of the modern physician. To better achieve this goal an understanding of the genetic basis for drug efficacy and toxicity is essential. Here we review the available information on the pharmacogenetics of drugs commonly used to treat rheumatic diseases in the hope that the applica...

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ژورنال

عنوان ژورنال: European Journal of Cancer Supplements

سال: 2013

ISSN: 1359-6349

DOI: 10.1016/j.ejcsup.2013.07.051